The San Francisco 49ers are 10.5-point favorites against the New York Giants.
Saquon Barkley will not play on Thursday Night Football.
Player prop projections have Purdy throwing for 226.5 passing yards in the game.
SAN FRANCISCO – The San Francisco 49ers are heavy -550 moneyline favorites against the New York Giants on Thursday Night Football. New York has -110 odds to cover a 10.5-point spread without Saquon Barkley.
San Francisco’s dominant defense and dynamic offense makes them the clear legal sports betting favorite against the Giants.
San Francisco 49ers vs New York Giants Betting Lines
San Francisco 49ers
New York Giants
The 49ers were 9-1 against the spread as a home favorite in 2022. They were also 3-1 against the spread as 9.5-point or greater favorites.
San Francisco cruised to a 23-point victory in Week 1 and would have covered the 7.5-point spread in Week 2 if the Los Angeles Rams didn’t kick a field goal as time expired.
Meanwhile, the Giants failed to cover the spread at legal NFL betting sites in their first two games. New York needed their biggest comeback since 1949 to defeat the Arizona Cardinals after dropping Week 1 40-0 to the Dallas Cowboys.
The Giants are in no position to cover the 10.5-point spread, especially without Saquon Barkley. Many believe Barkley will miss three weeks with a sprained ankle.
An MRI showed that Giants’ RB Saquon Barkley suffered an “ordinary” ankle sprain that now is expected to sideline him three weeks, per source.
— Adam Schefter (@AdamSchefter) September 18, 2023
With such a large spread and short -550 moneyline odds for the 49ers, other betting value is available with Brock Purdy player props.
Brock Purdy Passing Props
The legal California sports betting sites have Purdy projected for 226.5 passing yards on Thursday night. He threw under 226.5 passing yards in both games this season.
Brock Purdy Passing Yards Prop
Over 226.5 Passing Yards -115
Under 226.5 Passing Yards -115
The 49ers dominated their way to victory in Week 1 and 2, making it unnecessary for Purdy to throw the ball later in the game. The under with -115 odds at legal NFL betting is the best bet with San Francisco heavily favored again for Thursday Night Football.
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News tags: Brock Purdy | California | football | NFL | NY Giants | San Francisco 49ers | Saquon Barkley
Zach graduated from Florida State University with a degree in Writing, Editing, and Media. Zach is interested in the legalization aspect of sports betting and enjoys participating in DFS. He has a passion for sports writing and most enjoys writing about football and baseball both professional and collegiate.